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← Trials
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Neonatal Platelet Transfusion Threshold Trial

RecruitingNAAges 1 Hour - 48 HoursAllNICHD Neonatal Research Network
NCT06676904 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The objective of the NeoPlaTT trial is to test whether, among extremely preterm infants born at 23 0/7 to 26 6/7 weeks' gestation, a lower platelet transfusion threshold, compared to a higher threshold, improves survival without major or severe bleeding up to 40 0/7 weeks' postmenstrual age (PMA).

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📋 Eligibility rules (as published)
Inclusion Criteria: * Gestational age of 23 0/7 to 26 6/7 weeks * Postnatal age of \< 48 hours Exclusion Criteria: * Comfort care or withdrawal of care planned * Neonatal alloimmune thrombocytopenia or suspected/confirmed congenital platelet or bleeding disorder * Receipt of platelet transfusion * No receipt of Vitamin K * Parents/guardian decline consent
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What it tests

  • Higher Platelet Transfusion Threshold
  • Lower Platelet Transfusion Threshold
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Where

20 sites
University of Alabama at Birmingham
Birmingham, United States
Stanford University
Palo Alto, United States
Sharp Mary Birch Hospital for Women & Newborns
San Diego, United States
University of Colorado
Aurora, United States
Emory University
Atlanta, United States
Northwestern Lurie Children's Hospital of Chicago
Chicago, United States
University of Iowa
Iowa City, United States
Beth Israel Deaconess Medical Center
Boston, United States

…and 12 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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