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Liquid biopsiEs fOr luNg AllogRaft Damage classificatiOn - LEONARDO

Recruitingn/aAges 18 Years - anyAllJesper Magnusson
NCT06679257 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

LTx has the shortest survival of all solid organ transplants. The complex and time-demanding diagnostics of allograft dysfunction are a significant reason for this. The current study aims overarchingly to improve survival after lung transplantation (LTx) through precise and fast diagnostics. The specific aim is to develop direct-to-clinical implementation biomarkers for the most important aspects of long-term survival after LTx. An in-house-developed PCR-based cell-free-DNA methodology (cf-DNA) will be used for allograft damage and combined with specific other biomarkers to identify damage type. The current clinical golden standard for damage identification will be performed at every sampling instance. The research will be a single-centre prospective observational cohort study. The control samples at all time points will consist of the samples without allograft damage. Blood will be dr

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📋 Eligibility rules (as published)
Inclusion Criteria: * Luing Transplanted and followed up within the reach of the study paricipating centres. A good understanding to read and write within the languages in which the consent is provided. Exclusion Criteria: * Not Lung Transplanted or not followed up within the reach of the study paricipating centres. No good understanding to read and write within the languages in which the consent is provided.
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What it tests

  • cell-free dNA
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Where

1 site
Sahlgrenska University hospital
Gothenburg, Sweden
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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