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Effects of Partial Sleep Deprivation on Cardiac Output During Cycling

RecruitingNAAges 18 Years - 50 YearsAllUniversity of Guelph
NCT06679543 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to determine if attenuations in cardiac output drive the blunted blood pressure response during cycling exercise following a night of partial sleep deprivation in young healthy adults (%50 females). The secondary outcome is to assess sex differences. The main questions it aims to answer are: * Do reductions in plasma volume drive reductions in cardiac output and therefore blood pressure during exercise following a night of partial sleep deprivation? * Do sex differences exist? Participants will: * Visit the lab after a night of normal sleep and a night of partial sleep deprivation. * Keep a daily diary of their sleep and food/beverage intake. * Perform maximal and submaximal exercise on a cycle ergometer.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Free of known cardiovascular or metabolic diseases or sleep disorders * No history of smoking (within the past 3 months) * Able to engage in physical activity assessed through the physical activity readiness questionnaire (PAR-Q+) * No prescription of chronic medications other than oral contraceptives * Able to abide by sleep protocols for all visits * Individuals who are not allergic to ultrasound gel * Individuals who are not pregnant Exclusion Criteria: * Individuals diagnosed with cardiovascular or metabolic disease or sleep disorders * Has a history of smoking (within the past 3 months) * Not ready to engage in physical activity as assessed by the PAR-Q+ * Individuals prescribed chronic medications other than oral contraceptives * Unable to abide by sleep protocols for any testing visit * Allergic to ultrasound gel * Pregnancy
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What it tests

  • Partial sleep deprivation
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Where

1 site
University of Guelph
Guelph, Canada
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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