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Study of Normal Intestinal Development and Disease in Premature and Term Neonates

Recruitingn/aAges any - 2 YearsAllBoston Children's Hospital
NCT06681129 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Current research on early intestinal development is primarily performed in mouse models. While useful in many other ways, mouse models are not ideal for studying human intestine development as the timing of this process differs between the two species. Further, prior research has demonstrated that some proteins and pathways that are critical in human development have no clear role in mice. This study aims to improve the overall understanding of critical aspects of intestinal development in humans. In addition, this study will investigate the impact of intestinal diseases that are found in the early stages of life such as necrotizing enterocolitis (NEC).

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📋 Eligibility rules (as published)
Inclusion Criteria: * Any neonate or infant through 2 years of age having intestinal surgery or intestinal biopsies from an esophogastroduodenoscopy (EGD) or colonoscopy. Exclusion Criteria: * Children \> 2 years of age. * Infants 0-2 years old not undergoing GI surgery or intestinal scope with biopsy procedure.
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What it tests

  • Not listed
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Where

1 site
Boston Children's Hospital
Boston, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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