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The Impact of Local Anesthetic Solution Temperature on Epidural-related Maternal Fever

RecruitingNAAges 18 Years - anyFemaleThe First Affiliated Hospital of Soochow Universi…
NCT06682416 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study investigates how the temperature of local anesthetics affects maternal fever related to epidural analgesia during childbirth. The research is a prospective, randomized controlled trial involving 424 participants from two hospitals. The primary objective is to investigate the impact of local anesthetic solution temperature on intrapartum fever in parturients. Secondary goals include assessing the impact on the efficacy of epidural analgesia and various maternal and neonatal outcomes. Participants will receive either 37°C or 23°C anesthetic solutions, and data will be collected on fever rates, pain scores, and other health indicators. The study runs from January 2024 to December 2026.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Requesting epidural analgesia; 2. Aged 18 or older; 3. At least 37 weeks of gestation; 4. Those delivering vaginally. Exclusion Criteria: 1. Contraindications to epidural analgesia; 2. Pre-existing fever (≥38°C) before labor; 3. Use of NSAIDs or other types of antipyretics before labor; 4. Multiple pregnancy (carrying more than one fetus); 5. Fetal demise (stillbirth); 6. Severe preeclampsia; 7. Women who refuse to participate.
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What it tests

  • In the context of epidural analgesia, the temperature of the local anesthetic solution is elevated to 37°C utilizing a blood transfusion and infusion warmer.
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Where

2 sites
Ethical Committee of the First Affiliated Hospital of Soochow University
Suzhou, China
Suzhou Municipal Hospital
Suzhou, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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