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Comparison of Clinical Status of Individuals With COPD and Preserved Ratio Impaired Spirometry

Recruitingn/aAges 40 Years - anyAllHacettepe University
NCT06682832 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Despite the globally varying high prevalence rate of the PRISm phenotype, there are no guidelines for its diagnostic evaluation and management. Further studies are needed on appropriate approaches for individuals with PRISm to improve respiratory symptoms and prognosis. As research continues to evolve, PRISm needs to be recognized as a critical component of pulmonary assessments and at-risk individuals need to be provided with appropriate treatment and follow-up to prevent progression to COPD. There are no studies in the literature comparing PRISm, respiratory muscle strength, peripheral muscle strength and oxygenation, arterial stiffness, physical activity level and sleep level in COPD and healthy individuals. The aim of this study was to compare respiratory muscle strength, peripheral muscle strength and oxygenation, arterial stiffness, physical activity level and sleep level in PRISm,

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📋 Eligibility rules (as published)
Inclusion Criteria: PRISm group inclusion criteria; * Being \>40 years old, * Being diagnosed with PRISm, * Volunteering to participate in the study, * Not having any orthopaedic or neurological problems that may prevent participation in the measurements, * Co-operation with measurements Inclusion criteria for the COPD group; * Being \>40 years old, * Being diagnosed with COPD, * To be clinically stable, * Volunteering to participate in the study. Inclusion criteria for healthy individuals; * Being \>40 years old, * Volunteering to participate in the study, * No known chronic health problems, * To be able to co-operate with the measurements. Exclusion Criteria: PRISm group exclusion criteria; * Being diagnosed with COPD, * Severe orthopaedic, neurological and cardiac diseases * Not volunteering to participate in the study Exclusion criteria for COPD group; * Severe orthopaedic, neurological and cardiac diseases, * Being in COPD exacerbation period, * Not volunteering to participate in the study. Healthy individuals exclusion criteria; * Having a known chronic disease, * Not volunteering to participate in the study
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What it tests

  • Not listed
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Where

1 site
Hacettepe University
Ankara, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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