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โ† Trials
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Prevalence and Characteristics of Restless Leg Syndrome in Thai Patients With Parkinson's Disease

Recruitingn/aAges 18 Years - 80 YearsAllSiriraj Hospital
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In plain words

What the trial is, and whether it could suit you

Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by pathologic intraneuronal alpha-synuclein-positive Lewy bodies and neuronal cell loss. The cardinal clinical symptoms and signs of PD are bradykinesia, rigidity, tremor, postural instability, and freezing attacks. The prevalence of PD increases with age, affecting 1-2% of the population over the age of 65 years, and 3% of those over 85 years. Restless legs syndrome (RLS) represents disturbing symptoms in lower limbs that lead to the urge to move, occurring in rest periods. Movements can partially or completely relieve these abnormal feelings. In 2014, the International RLS Study Group (IRLSSG) established five mandatory criteria for the diagnosis of RLS. Several studies supported that RLS and PD may share pathophysiological mechanisms.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Patients with Parkinson's disease aged from 18 to 80 years who met the United Kingdom Parkinson's Disease Society (UKPDS) Brain Bank Diagnostic criteria. Exclusion Criteria: * Patients with atypical or secondary parkinsonism. * Patients with Mini-mental status exam (MMSE) less than 24 of 30. * Patients with secondary causes of restless leg syndrome including end-stage renal disease, iron deficiency anemia and pregnancy.
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What it tests

  • Screening for symptoms of restless leg syndrome
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Where

2 sites
Siriraj Hospital, Mahidol University
Bangkok, Thailand
Siriraj Hospital, Mahidol University
Bangkok, Thailand
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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