🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

The Importance of Non-essential Amino Acids for Maintaining Skeletal Muscle Protein Synthesis Rates in Healthy Young Men

RecruitingNAAges 18 Years - 35 YearsMaleMaastricht University Medical Center
NCT06687343 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

Background: Protein intake is important for maintaining skeletal muscle mass. These proteins consist of a collection of small building blocks which are called amino acids. There are two types of amino acids that are needed to build muscle: essential amino acids (EAA) and non-essential amino acids (NEAA). EAAs cannot be made in the body and must be consumed through foods, while NEAAs can be made within the body. However, if NEAA are not consumed through foods, the process of making NEAA in the body costs the body energy. It is still unknown what the impact of a diet containing too few non-essential amino acids is for muscle building and the body's energy metabolism. Objective: To determine if a diet lacking NEAA, with or without being replaced by additional EAA, influences muscle protein building and whole-body metabolism. Study design: Randomized, parallel design, double-blind, 10-day

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * Male * Age between 18 and 35 y inclusive * BMI between 22 and 30 kg/m2 * Non-smoker * Having given informed consent Exclusion Criteria: * Participating in a structured (progressive) exercise program * Smoker * Diagnosed GI tract disorders or diseases * Diagnosed musculoskeletal disorders * Diagnosed metabolic disorders (e.g. diabetes) * Cardiovascular disease * Hypertension (blood pressure above 140/90 mmHg) * Donated blood 3 months prior to test day * Use of any medications known to affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories). * Chronic use of gastric acid suppressing medication * Chronic use of anti-coagulants * Any intolerance to foods included in the standardized diet intervention * Any implants that would be a contra-indication for performing an MRI scan
💊

What it tests

  • EAA Supplement
  • NEAA Supplement
  • Maltodextrin Supplement
📍

Where

1 site
Maastricht University Medical Center
Maastricht, Netherlands
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy