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WAter Preparation in Crohn's Disease's Imagery

RecruitingNAAges 18 Years - anyAllUniversity Hospital, Toulouse
NCT06690632 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to compare distension quality and patient experience of water and polyethylene glycol preparation as oral contrast media in Magnetic Resonance Enterography (MRE) in patients with Crohn's disease. Thus, the main question it aims to answer is: Is water sufficient to interpret MRE from patients with Crohn's disease? Researchers will compare the standard protocol (polyethylene glycol) with water as bowel distension agent to see if it is possible to obtain a satisfying global distension of small bowel. Participants will undergo the same procedures as standard care adding questionnaires and replacing water as the bowel distension agent for the MRE for patient randomized into the experimental group.

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📋 Eligibility rules (as published)
Inclusion criteria: * Diagnosis of Crohn's Disease, * need for MRE (determined by patient's gastroenterologist) Exclusion criteria: * \< 18 years old, * inability to obtain an informed consent, * patient under guardianship or curatorship, allergy to PEG, * contraindication to MRE (pregnancy, pace maker, claustrophobia in particular), - contraindication to phloroglucinol administration (phenylcetonuria), * contraindication to gadolinium administration (kidney failure with glomerular filtration rate \< 30/mL/1.73m², pregnancy, allergy).
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What it tests

  • water preparation
  • polyethylene glycol preparation
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Where

1 site
CHU Toulouse
Toulouse, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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