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Physiological Effects of Lung Impedance Tomography-Guided and Plat Pressure-Guided Phigh During APRV in Patients With ARDS

RecruitingNAAges 18 Years - anyAllXiaoJing Zou,MD
NCT06696638 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study aims to investigate the effects of EIT-guided and Pplat-guided Phigh settings on regional ventilation and perfusion in ARDS patients during APRV, while also examining the impact of different Phigh settings on gas exchange, respiratory mechanics, and hemodynamics.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Diagnosed with ARDS according to the 2023 global new definition of ARDS. * Age ≥ 18 years. Exclusion Criteria: * Severe chronic obstructive pulmonary disease, severe asthma, pulmonary bullae, pneumothorax, subcutaneous emphysema, mediastinal emphysema, etc. · Contraindications for EIT, such as chest wound dressing, pacemaker implantation, defibrillator use, etc. * Pulmonary interstitial disease. * Uncorrected shock of various types. * Intracranial hypertension. * Pregnant and postpartum women.
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What it tests

  • EIT-guided Phigh settings during APRV
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Where

1 site
Wuhan Union hospital
Wuhan, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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