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PD1 Inhibitors Combined With Clostridium Butyricum for Urothelial Carcinoma

RecruitingPhase 2Ages 18 Years - anyAllThe First Affiliated Hospital with Nanjing Medica…
NCT06696742 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study intends to explore whether the combination of Clostridium butyricum can improve the current situation of poor anti-PD1 treatment effect in patients with bladder cancer.

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📋 Eligibility rules (as published)
Inclusion Criteria: For Neoadjuvant therapy: * T2-T4aN0M0 bladder patients For Adjuvant therapy: * Postoperative pathological stage T3-T4 and/or lymph node metastasis were positive. Exclusion Criteria: * The researchers evaluated the patients who could not tolerate radical surgery; * Previously received systemic chemotherapy or immunotherapy; * There are active autoimmune diseases requiring systemic treatment or other diseases requiring long-term use of a large number of hormones and other immunosuppressants; * Have had major surgery or major trauma within 28 days before joining the group; * Vaccinated with live vaccine within 28 days before joining the group.
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What it tests

  • Clostridium Butyricum Tablets
  • Cisplatin
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Where

1 site
The First Affiliated Hospital of Nanjing Medical University
Nanjing, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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