AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

โ† Trials
๐Ÿงช

Feasibility of Using the Neovent in Low-Resource Settings

RecruitingNAAges 1 Minute - 28 DaysAllTina Slusher
๐Ÿ’ฌ

In plain words

What the trial is, and whether it could suit you

Breathing problems are a leading cause of newborn death/sickness worldwide but most of deaths are in low resources areas. Over 99% of newborn death is in countries with limited healthcare resources like Nigeria and Nepal. Background For newborns who have trouble breathing, breathing with a machine that does not require an invasive breathing tube but only small nasal tubes is associated with lower rates of lung disease and less pneumonia or lung disease than newborns who have a breathing tube going into their lungs to help their breathing. Nasal Intermittent Positive Pressure Ventilation (NIPPV) is often used in high resource countries, but these machines are expensive. NIPPV gives many newborns the extra support needed to help with trouble breathing by providing extra pressure to help more air/oxygen get into their lungs. Neovent was designed to provide NIPPV at a much lower cost than m

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Infants โ‰ค 28 days and \> 30weeks and/or \> 1000 gram (birthweight or admission weight if birthweight unknown) * Mild to moderate respiratory distress (Downes' score 2 - 7) * Parental/guardian permission (informed consent). Exclusion Criteria: * Congenital abnormality such that noninvasive positive pressure ventilation would be contraindicated (e.g. diaphragmatic hernia, cleft palate, tracheo-esophageal fistula) * Need for immediate surgical intervention * Suspected neuromuscular abnormality as evidenced by decreased tone * Suspected cyanotic congenital cardiac disease or cardiac instability * Severe life-threatening condition such that the doctor caring for the patient believes survival of patient will be less than 24 hours and/or parents request withdrawal of care
๐Ÿ’Š

What it tests

  • bilevel ventilation with the Neovent
๐Ÿ“

Where

2 sites
United Mission Hospital-Tansen
Tฤnsen, Nepal
Ahmadu Bello University
Zaria, Nigeria
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
๐Ÿ›ก๏ธ

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it โ€” not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use ยท Privacy