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Effect of Silver Diamine Fluoride Application on Oral Microbiome of Healthy Pediatric Patient

RecruitingPhase 4Ages 4 Years - 12 YearsAllKing Abdulaziz University
NCT06699199 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This clinical trial aims to learn more about the working mechanism of an antimicrobial agent used to manage dental caries, especially in young, uncooperative children. It will also provide a deeper insight into different products of the same agent and its effectiveness in Arresting dental caries. The main questions it aims to answer are: What is the clinical impact of silver diamine fluoride application in caries-active children? What is the antimicrobial effect of silver diamine fluoride in oral microbial inhabitants? Researchers will compare silver diamine fluoride (SDF)only and silver diamine fluoride+ potassium iodide(SDF+KI) to see which materials substantially affect on dental caries and oral microbial inhabitants Participants/Parent will: The parent will fill out a comprehensive data sheet for the child (childhood and current dental and medical history) Visit the dental clinic

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📋 Eligibility rules (as published)
Inclusion criteria * Healthy patients. * Patients within 4-10 years of age. * The presence of at least one deciduous tooth with a caries lesion that is directly accessible (cavitates) Exclusion Criteria: * Presentation of irreversible pulpititis or necrosis• The extensive lesion was restored. * The surface of the lesion was hard and smooth. * Children with inherited or systemic conditions. * Children with a substantial medication history or those who have taken antibiotics within the previous three months. * Children who have undergone topical fluoride treatment within the previous 2 weeks.
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What it tests

  • Silver diamine Fluoride 38%
  • Silver diamine fluoride- potassium iodide
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Where

1 site
University Dental hospital of King Abdulaziz University
Jeddah, Saudi Arabia
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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