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Frequency of Interrupting Sitting and Cognitive Function

RecruitingNAAges 18 Years - 35 YearsAllMaastricht University Medical Center
NCT06700187 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Rationale: Sedentary behavior (SB) has been associated with impaired cognitive function in elderly, and negatively impacts glucose metabolism. Interrupting sitting with physical activity (PA) bouts may exert beneficial effects on cognitive function via an improved glucose metabolism. Nevertheless, the impact of breaking up prolonged sitting with various frequencies of PA bouts remains unexplored in young sedentary adults. Moreover, we hypothesize that the pattern of the breaks modifies the effects. Thus, randomized controlled trials (RCTs) are highly needed to investigate the effects of interrupting sitting with different frequencies of PA on cognitive function and glucose metabolism. We now hypothesize that interrupting sitting with different frequencies of walking breaks differentially affects cognitive function and glucose metabolism. Objective: The aim is to investigate the effects

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📋 Eligibility rules (as published)
Inclusion Criteria: * Men and women aged 18-35 years; * BMI between 18.5-24.9 kg/m2; * SB, i.e. sitting for an average of at least 9 hours per day; * Physically inactive, i.e. engaging in exercise for less than 2 to 3 times per week; * Stable body weight (weight gain or loss \< 3 kg in the past three months); * Willingness to engage in four 6-hour laboratory visits; * No difficult cannulation. Exclusion Criteria: * Not sedentary, i.e. sitting for less than an average of 9 hours per day; * Physically active, i.e. engaging in exercise for more than 3 times a week; * Abuse of drugs; * Use medication to treat BP, lipid, or glucose metabolism; * Pregnant females.
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What it tests

  • Interrupting sitting with walking breaks
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Where

1 site
Nutrition and movement science
Maastricht, Netherlands
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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