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The Clonal Hematopoiesis & Inflammation in Vasculature Registry and Biorepository

Recruitingn/aAges 18 Years - anyAllVanderbilt-Ingram Cancer Center
NCT06701214 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study will investigate the association between clonal hematopoiesis and other conditions. Clonal hematopoiesis (CH) refers to the mutations in a person's stem cells which commonly affect people as they get older. These mutations have notably been linked to increased risk of certain cancers as well as increased risk of heart disease.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patient greater than or equal to 18 years old at time of consent * Able to provide informed consent * Idiopathic cytopenia (ICUS) or idiopathic cytoses (elevated blood counts without disease or explanation); clonal cytopenia of undetermined significance (CCUS), clonal hematopoiesis of indeterminate potential (CHIP) or individuals at higher risk for clonal hematopoiesis (ex. patients with known diagnosis of solid tumors or cardiovascular disease) Exclusion Criteria: * Unable to provide consent * Diagnosis of active hematologic malignancy. For example, a diagnosis of CMML, AML, MDS, MPN; History of hematologic malignancy is NOT exclusionary if in complete remission (e.g. previous myeloma or lymphoma)
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What it tests

  • Blood collection
  • Saliva collection
  • Bone marrow collection
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Where

1 site
Vanderbilt University/Ingram Cancer Center
Nashville, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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