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Assessing Habitual, Goal-Directed, and Pavlovian Influences in Alcohol Use Disorder

Recruitingn/aAges 18 Years - 65 YearsAllTechnische Universität Dresden
NCT06701500 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The first aim of this study is to establish the role of maladaptive reliance on habits for impaired control in addiction, employing a novel task - the Action-Sequence-Task (AST), which assesses interference between habitual and goal-directed control. The AST, along with the developed computational model, will be employed to test whether participants with Alcohol Use Disorder (AUD) and control participants differ with respect to task performance and estimated model parameters. The investigators hypothesize stronger habitual behavior (increased habitual tendency) and an increased susceptibility to conflict between habitual and goal-directed control, measured as increased interference, are associated with AUD. The second aim of the study is to understand whether Pavlovian-to-Instrumental Transfer (PIT) reflects more of a controlled, goal-directed process, or a more automatic, habitual proc

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📋 Eligibility rules (as published)
Inclusion Criteria: * 18-65 years of age * AUD subjects only: meet 4 or more criteria for DSM-5 alcohol use disorder * Sufficient motor skills and visual acuity to use PC * Ability to consent to the study and complete the questionnaires * Sufficient German skills Exclusion Criteria: * Lifetime diagnosis of DSM-5 bipolar disorder, schizophrenia or schizophrenia spectrum disorder * Current diagnosis of severe major depression according to DSM-5, or presence of suicidal intention * Pregnancy * Severe withdrawal symptoms * Acute drug intoxication at the appointments
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What it tests

  • Pavlovian-to-instrumental transfer (PIT) paradigm
  • Action Sequence Task (AST)
  • Basic psychological assessment (interview)
  • Basic psychological assessment (questionnaires)
  • Neuropsychology tests
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Where

1 site
Department of Psychiatry and Psychotherapy, Technische Universität Dresden
Dresden, Germany
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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