The Efficacy of Transcutaneous Pulsed Radiofrequency Acupuncture for Knee Osteoarthritis

Inclusion Criteria: * Age from 45 to 85 year-old with knee pain for more than six months * Fulfill the combined clinical and radiographic criteria of knee OA established by the American College of Rheumatology with a Kellgren and Lawrence score of 2 or greater * Pain score above 3 (range 0-10 on the visual analog scale; higher scores indicate greater pain * Could participate in 4 weeks of treatment and 3 months of follow-up Exclusion Criteria: * Knee OA combined with any infection, inflammation, autoimmune disease, or fracture * History or underlying disease that would affect posture and balance, such as malignancy, dizziness, vertigo, or stroke * Ever underwent any type of knee operation or internal fixation * Pregnant or planning to become pregnant * Receiving other treatment for knee OA in previous 3 months * History of epilepsy, electronic devices implanted in the body * Active infection at the stimulator contact site * Lack of informed consent * Any other reason thought likely to result in inability to complete the trial