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APPI-Cost Trial for Perforated Appendicitis

RecruitingPhase 4Ages 18 Years - anyAllThe University of Texas Health Science Center, Ho…
NCT06705842 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The purpose of this study to assess the clinical effectiveness and cost-effectiveness of povidone-iodine (PVI) irrigation in perforated appendicitis, to investigate barriers and facilitators to future implementation of PVI irrigation, and to collect costs and clinical and patient-reported outcomes among patients with non-perforated appendicitis.

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📋 Eligibility rules (as published)
Eligibility for Enrollment Inclusion Criteria: * Plan to undergo appendectomy for acute appendicitis Exclusion Criteria: * Preoperative hemodynamic instability requiring ongoing infusion of vasopressors * Allergy to iodine * Uncontrolled hyper- or hypothyroidism * Renal dysfunction * Pregnant or breastfeeding * Primary language neither English nor Spanish * Lack of functioning telephone or email account * Incarcerated or in police custody Eligibility for Randomization Inclusion Criteria: * Enrolled in study preoperatively * Intraoperative diagnosis of perforated appendicitis Exclusion Criteria: * Non-perforated appendicitis
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What it tests

  • PVI
  • Usual Care
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Where

1 site
The University of Texas Health Science Center at Houston
Houston, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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