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Depressive Symptoms After Cardiac Surgery

Recruitingn/aAges 18 Years - 90 YearsAllRoland von Känel
NCT06706323 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The primary goal of this project is to develop a predictive model for clinically significant depressive symptoms (CSDS) in patients undergoing coronary artery bypass graft (CABG) surgery, using pre- and perioperative data. CSDS occur in about 30 percent of CABG patients, which is four times higher than in the general population. These symptoms are linked to poor quality of life and increased morbidity and mortality. The aim is to create a model that can identify patients at risk for postoperative depression. This tool could help clinicians make informed decisions and take preventive measures to manage depression after surgery.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Elective Off-Pump CABG or CABG, either isolated or combined with valve intervention * Men and women, aged between 18 and 90 years * Sufficient knowledge of German language in reading and understanding * Oral and Signed consent form * Ability and Willingness to follow the study protocol Exclusion Criteria: * Cognitive impairment according to a score of ≤ 7 (maximum score = 9) on a modified version of a short version of the Mini-Mental State Examination and the Brief Interview for Mental Status * Any serious comorbid non-cardiac medical condition likely to cause death within 1 year (e.g. metastatic cancer) * Active psychotic symptoms (assessed with two items from the Youth Psychosis At Risk Questionnaire), substance abuse and/or dependence within the past 6 months (assessed with a single-item questionnaire), and/or active suicidal ideations (assessed with a single item from the M.I.N.I.). * Acute or emergency CABG
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What it tests

  • Not listed
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Where

2 sites
Stadtspital Zürich (City Hospital Zurich) Triemli
Zurich, Switzerland
University Hospital Zurich (USZ)
Zurich, Switzerland
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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