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Noninvasive Brain Stimulation in Adult Amblyopia

RecruitingNAAges 18 Years - 55 YearsAllMidwestern University
NCT06712849 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this randomized controlled trial is to investigate the effectiveness of non-invasive brain stimulation in treating adults with amblyopia. The main questions it aims to answer are: 1. What are the effects of non-invasive brain stimulation on neuronal plasticity in the visual cortex of adults with amblyopia, and does it produce lasting changes? 2. Do cumulative sessions of non-invasive brain stimulation influence neural plasticity and higher-order visual functions in adults with amblyopia? The investigators hypothesize that non-invasive brain stimulation will show a positive cumulative effect after five (5) consecutive days of stimulation on visual perception and function in adults with amblyopia. Participants will be randomized into one of two treatment groups: 1. High-frequency transcranial random noise stimulation (hf-tRNS). 2. Sham stimulation. Researchers will compare

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adults between 18 and 55 years of age * Formal diagnosis of amblyopia in one or both eyes of any etiology Exclusion Criteria: * History of optic nerve disease, including glaucoma and optic neuritis * History of neurological conditions, including demyelinating disease or stroke * Presence of metal or electronic implants in or on the body, including pacemakers * Taking medications that can affect normal neurological function, including antipsychotics, antiepileptics, and opioids
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What it tests

  • Sham Transcranial Random Noise Stimulation
  • High Frequency Transcranial Random Noise Stimulation
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Where

1 site
Midwestern University Eye Institute
Downers Grove, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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