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Tissue Analysis of Liver Grafts as a Predictor of Transplant Outcome.

RecruitingNAAges 18 Years - anyAllIRCCS Azienda Ospedaliero-Universitaria di Bologna
NCT06717542 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Despite the good clinical results in terms of outcome with the application of HOPE prior to liver transplantation, very little is still known about the phenotypic and molecular changes that occur during perfusion/preservation during HOPE, particularly with regard to endothelial trophism and activation. Delving into these aspects would be very useful to allow personalised perfusion treatments in the future, thus improving the outcome of transplantation.

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📋 Eligibility rules (as published)
Inclusion Criteria: * For Donors: Availability of enough tissue for histological, immunohistochemical and RT-PCR analysis. * HOPE performed on the liver graft prior to transplantation. * For Recipients: * Availability of enough tissue for histological, immunohistochemical and RT-PCR analysis. * Age greater than/equal to 18 years. Exclusion Criteria: * None
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What it tests

  • histochemical and immunohistochemical analysis
  • RT-PCR
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Where

1 site
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Bologna, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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