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Efficacy of Adenosine as Compared to Verapamil in Paroxysmal Supraventricular Tachycardia (pSVT) Patients

RecruitingPhase 3Ages 18 Years - 70 YearsAllRashid Latif Medical College
NCT06717685 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Supraventricular tachycardia (SVT) is a term widely used to describe tachycardial dysrhythmias, paroxysmal SVT (PSVT) is a narrow term including only AV nodal re-entrant tachycardia (AVNRT) and atrioventricular re-entrant tachycardia (AVRT), both of which can cause discomfort and, in some cases, life-threatening symptoms. Usually Carotid sinus massage is done to lower the pulse rate and after the standard time specific verapamil dose is administered. In this study after carotid sinus massage Conventional Valsalva or modified Valsalva maneuver will be randomly applied. In case, the normal sinus rhythm (NSR) is not achieved then verapamil of or adenosine dose will be administered to the patients after after taking the consent.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Stable SVT (not requiring cardioversion, fully conscious, maintaining systolic blood pressure of \>90mmHg) * Alert enough and able to give consent * Able to lie flat and non-painful legs during passive leg raising Exclusion Criteria: * Unstable SVT (Semiconscious, drowsy, breathless, systolic BP \<90mmHg) * Not able to give consent * Orthopnea causing inability to lie flat * Atrial fibrillation/atrial flutter * Recent MI (within last 7 days) * Ongoing ischemia as indicated by chest pain or ST segment depression/elevation in ECG * Aortic stenosis * All trimesters of pregnancy
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What it tests

  • Adenosine
  • Verapamil Injection
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Where

1 site
Punjab Institute of Cardiology
Lahore, Pakistan
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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