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Robotically Assisted Surgery For Perihilar Cholangiocarcinoma: A Prospective Study

Recruitingn/aAges 18 Years - anyAllAzienda Ospedaliera di Padova
NCT06720883 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Cholangiocarcinoma (CCA) represents the most common biliary tract malignancy, and the second most common primary hepatic malignancy, accounting for 15% to 20% of primary liver tumours. Perihilar cholangiocarcinoma (pCCA) involves the biliary confluence with or without involvement of the right and left hepatic ducts. Complete resection with negative histologic margins is the only chance of cure and the most robust predictor of long-term survival for patients affected by any type of locally advanced CCA. However, the proximity of perihilar tumors to vital structures makes curative excision technically difficult. Minimally invasive approaches are progressively spreading in liver surgery units worldwide. Significant advantages of minimally invasive liver resections, if compared to open one, have been diffusely shown, such as shorter hospital stay and possibility of complex reconstructive p

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age≥18 years * Histologically proven pCCA or highly presumed bile duct malignancy with difficulties to obtain histological evidence with negative Immunoglobulin G4 (IgG4 sample) * Preoperative staging work up performed by abdomen enhanced CT scan. * The subject understands the nature of this trial and is willing to comply. * Ability to provide written informed consent. * Patients treated with curative intent in accordance to international guidelines Exclusion Criteria: * Distant metastases: peritoneal carcinomatosis, liver metastases, distant lymph node metastases, involvement of other organs. * Previous radiotherapy * Vascular encasement * Patients with high operative risk as defined by the American Society of Anesthesiologists (ASA) score\>4. * Synchronous malignancy in other organs. * Palliative surgery
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What it tests

  • Major hepatectomy
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Where

1 site
Azienda Ospedaliera di Padova
Padova, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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