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Comparison of Cloxacillin and Benzylpenicillin in Penicillin Susceptible S. Aureus Bacteraemia

RecruitingPhase 4Ages 18 Years - anyAllRegion Skane
NCT06726395 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this study is to investigate if benzylpenicillin is a better treatment option than cloxacillin in patients with penicillin-susceptible Staphylococcus aureus bacteraemia.

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📋 Eligibility rules (as published)
Inclusion Criteria: Aged ≥18 with penicillin susceptible S. aureus bacteraemia (PSSA), and able to provide written informed consent. Exclusion Criteria: * allergy to penicillin, * inability to give informed consent, * concomitant growth of other clinically significant bacteria in blood cultures * neutropenia -≥ 96h with prior antibiotics * When the per oral follow up medication can not be flukloxacillin or penicillinV/Amoxicillin (ie prosthetic joint infection) * Patients in terminal palliation, where death is expected within 7 days. * Where the treating physician believes cloxacillin is not a first-line treatment.
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What it tests

  • Penicillin G_1200mg
  • cloxacillin
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Where

1 site
Skånes universitetssjukhus, Region Skåne
Lund, Sweden
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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