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โ† Trials
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Cognitive Rehabilitation for Veterans With MDD-related Cognitive Functioning Deficits

RecruitingNAAges 18 Years - anyAllPortland VA Medical Center
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In plain words

What the trial is, and whether it could suit you

Individuals with depression often describe difficulties with memory, attention, concentration, and overall cognitive functioning, which can persist even after mood episodes get better, and can affect treatment and health outcomes. The primary objective of this pilot clinical trial is to evaluate the feasibility and acceptability of a manualized, 8-week, Compensatory Cognitive Training (CCT) intervention for Veterans who received treatment for MDD in the past year and have persistent cognitive functioning deficits. The investigators will compare Motivationally Enhanced Compensatory Cognitive Training for Major Depressive Disorder (ME-CCT-MDD) to a robust comparator, Goal-focused Supportive Contact (GSC), to evaluate differences in outcome measures. The investigators hypothesize that Motivationally Enhanced Compensatory Cognitive Training for Major Depressive Disorder (ME-CCT-MDD) will b

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: 1. Veterans 18 years of age or older 2. Self-reported concerns about cognitive functioning deficits or clinical concerns about cognitive functioning deficits documented in EHR 3. meets DSM-5 criteria for MDD and receiving treatment for this diagnosis at the Portland VA within the past year 4. moderate or greater depressive symptoms as assessed by a PHQ-9 score โ‰ฅ 10 5. current cognitive functioning deficits as determined by performance on at least two measures in one cognitive domain (i.e., memory, attention/processing speed, language, executive functioning) falling โ‰ฅ1 SD below their age-appropriate norms in the absence of memory impairment. Exclusion Criteria: 1. impaired capacity to understand study risks and benefits 2. history of TBI as defined by American College of Rehabilitation Medicine and VA/DoD criteria 3. meets DSM-5 criteria for a substance use disorder other than nicotine use disorder in the past 6 months 4. meets DSM-5 criteria for dementia, psychotic disorder, or "with psychotic features" specifier 5. active suicidal intent with significant clinical risk 6. auditory or visual impairments that would prevent ability to participate in cognitive rehabilitation group or assessments. Eligibility will be established by electronic medical record review conducted by study staff and will be confirmed by the Veteran during the initial phone call.
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What it tests

  • Motivationally Enhanced Compensatory Cognitive Training for Major Depressive Disorder (ME-CCT-MDD)
  • Goal-focused Supportive Contact
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Where

1 site
Portland VA Medical Center
Portland, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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