🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Does Starting Feeds on the First Day of Life Help Premature Infants Reach Full Volume Feeds Sooner?

RecruitingNAAges 1 Minute - 6 HoursAllUniversity of Tennessee
NCT06731439 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

Feeding advancements in ELBW infants have evolved over decades. The fear of causing mortality and morbidity, notably NEC, have made providers cautious when advancing feeds. ELBW infants initially remained NPO for several days before initiating trophic feeds. However, data then showed that there was no increase in mortality and morbidity if trophic feeds were initiated earlier. Then data showed that a short duration of trophic feeds did not increase mortality and morbidity when compared to a prolonged duration. More recent data showed that enteral feeding should be initiated early, preferably within 24 hours of birth, because it may promote feeding tolerance, shorten the time to reach total enteral feeding, and reduce the incidence of extrauterine growth restriction and late onset sepsis without increasing the risk of developing NEC. The management of enteral nutrition in ELBW infants is

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: 1. All infants less than or equal to 1000 g 2. Clinical care team in agreement with patient's participation 3. All mothers with pregnancies with EFW close to 1000g or less. Exclusion Criteria: 1 congenital malformations that may affect gastro intestinal perfusion 2 Clinically progressing towards imminent death 3 congenital gastrointestinal obstructions 4 Mothers unlikely to deliver infants ≤ 1000g 5 Infant on pressors other than dopamine given at \< 5mcg/kg/min. Dopamine is an exclusion if administered at a dose exceeding 5mcg/kg/min. 6 Mothers who are not in a sound mental state to be consented either to their critical condition, intubated, sedated, for examples 7 Mothers who are critically ill where by it is felt that mom will not be able to participate in the consent
💊

What it tests

  • Starting feeds within 6 hours of life
  • Standard feeding protocol
📍

Where

1 site
Regional One Health
Memphis, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy