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Omega-3 Fatty Acids and Subconcussive Head Impacts

RecruitingNAAges 18 Years - 30 YearsAllIndiana University
NCT06736925 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The purpose of the proposed double-blind, randomized placebo-controlled trial is to understand how supplementation with fish oil \[docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA)\] promote brain health against soccer heading. The study involves taking DHA+EPA or placebo, questionnaires, blood draws, brain imaging, tests to evaluate heart function, and soccer headings.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Between age 18-30 * Current or former soccer player * At least 5 years of soccer heading experience * Have internet access * Willing to commit to avoid any sport activity that purposefully uses one's head to maneuver during the study period (American football, ice-hockey, rugby, wrestling, and soccer heading). Exclusion Criteria: * Any head or neck injury within 6 months before the study * Implanted metal/magnetic devices (e.g., orthodontic braces * Diagnosed autonomic or cardiovascular diseases (e.g., hypertension) * Consuming oily fish (2 servings or more/month: salmon, bluefin, swordfish, anchovies) * Allergy to fish or shellfish * Consuming omega-3 FA supplements including plant-based (e.g., flaxseed) in the past 3 months. * Pregnancy
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What it tests

  • Omega-3 Fatty Acids (EPA plus DHA)
  • Organic soybean oil
  • Soccer Heading Model
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Where

1 site
Indiana University School of Public Health
Bloomington, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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