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Recompensation in Alcohol Related Hepatitis

RecruitingNAAges 18 Years - anyAllNina Kimer
NCT06740318 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Genetic activity and metabolic changes may be part of the pathogenesis in alcohol related hepatitis. We do not know exactly how alcohol cessation affects liver functions and metabolism. The aim of this study is to assess the impact of alcohol cessation in patients with alcohol related hepatitis and gain knowledge of the metabolic and genetic functions of the liver during remission and recompensation from alcohol related hepatitis. The study will assess 1. The effect of alcohol cessation on the liver. 2. The biological mechanisms involved in healing after alvohol-cessation 3. The effect of motivational enhcament therapy in alcohol cessation after alcohol related hepatitis. 4. The metabolic changes of lipids and proteins in the liver Participants are offered motivational enhancement therapy and standard of care.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Clinical suspicion of AH, supported by biochemistry (bilirubin 50 mmol/l or higher) and ultrasound or other imaging techniques. * Informed written consent. Exclusion Criteria: * People where the diagnosis of AH is questioned with reasonable doubt. * Withdrawal of informed consent. * Persons eligible for inclusion where the investigational program is delayed or not initiated within two months after the diagnosis of suspected AH. * Persons with hepatocellular carcinoma
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What it tests

  • Motivational enhancement therapy
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Where

1 site
University Hospital Hvidovre
Hvidovre, Denmark
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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