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โ† Trials
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Biomarkers/Biotypes, Course of Early Psychosis and Specialty Services

Recruitingn/aAges 18 Years - 40 YearsAllBeth Israel Deaconess Medical Center
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In plain words

What the trial is, and whether it could suit you

The Biomarkers/Biotypes, Course of Early Psychosis and Specialty Services (BICEPS) study aims to understand the early stages of psychotic disorders like Schizophrenia, Schizoaffective Disorder, and Bipolar I Disorder. It involves gathering mental health information, brain scans (MRI), eye movement patterns (Eye-Tracking), and brain electrical waves (EEG) data from individuals who have experienced these disorders in recent years. Participants will be involved for about a year, with four visits over this period. Screening procedures, lasting approximately 3 hours, include tests for drug use, a pregnancy test for eligible women, clinical interviews about feelings and experiences, psychiatric and family history interviews, and a medical history review. Research procedures for eligible participants include DNA collection, a neuropsychological test battery, EEG, eye-tracking, and MRI. These pr

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Males and females, all races and ethnicities * 18-40 y/o * Meet DSM-5 criteria for a psychotic disorder, i.e. schizophrenia, schizophreniform, schizoaffective disorder, or bipolar I disorder or major depression with psychotic features, delusional disorder or psychosis N.O.S. * Able to read, speak, and understand English * Able and willing to provide written informed consent, and willing to commit to the study protocol * Illness duration from psychosis onset less than or equal to 4 years * At baseline only: receiving both psychopharmacology and psychotherapy Exclusion Criteria: * Estimated premorbid intellectual ability \<70 (WRAT-4, Word Reading subtest, age-corrected standardized score) * Neurological or medical disorder that may affect brain function (seizure disorder, traumatic brain injury with a loss of consciousness greater than or equal to 30 min, history of stroke, AIDS, etc.) * Psychoses secondary to substance use i.e., Comorbid DSM-5 diagnosis of alcohol or substance use disorders that may explain the diagnosis of psychotic disorders (individuals with cannabis use disorders unrelated to psychosis onset will be allowed. Participants encouraged to abstain from substances for 24 hours prior to lab visits) MRI-Specific Exclusion Criteria: * Pregnant women * Presence of ferromagnetic objects in body * Weight or body size exceeding scanner capacity (\>300 lbs) * Claustrophobia
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What it tests

  • Not listed
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Where

6 sites
Hartford Hospital
Hartford, United States
University of Georgia
Athens, United States
University of Chicago Medical Center
Chicago, United States
McLean Hospital
Belmont, United States
Beth Israel Deaconess Medical Center
Boston, United States
University of Texas Southwestern Medical Center
Dallas, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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