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Evaluating Perioperative Outcomes: Dexmedetomidine vs Lignocaine in Laparoscopic Chlolecystectomy

RecruitingPhase 2, Phase 3Ages 20 Years - 70 YearsAllSahiwal medical college sahiwal
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In plain words

What the trial is, and whether it could suit you

Nowadays laparoscopic surgery is the first choice for many surgeries. Such surgeries have revolutionized the surgical practice and has markedly reduced the incidence of intraoperative and postoperative complications. To minimize these side effects associated with the use of opioids, various methods have been adopted. Recently, different trials have highlighted the possible role of dexmedetomidine and lignocaine in providing postoperative analgesia and attenuating hemodynamic response. Literature showed conflicting results regarding both these drugs. So, we want to find the evidence for local setting. This Randomized Controlled Trial will be done at Department of Anesthesia, Sahiwal teaching hospital, Sahiwal for 12 months. Sample size of 140 cases; 70 cases in each group will be included through non-probability consecutive sampling. Then patients will be divided in two groups by using co

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: 1. Patients of age 20-70 years 2. Both gender 3. Laparoscopic cholecystectomy under general Anaesthesia 4. ASA I-II. Exclusion Criteria: * Emergency surgery * Patients with history of allergic reaction to trial drugs * Patients with cardiovascular disease, sickle cell disease, psychiatric disorder, peripheral vascular disease, and neurological diseases (on medical record) * Anemia * Patient on TCA or Beta blocker drugs. * Uncontrolled hypertension (Pโ‰ฅ160/100 mmHg) * Uncontrolled diabetes mellitus * Obesity BMI \> 35
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What it tests

  • inj. dexmedetomidine infusion @ 0.2-0.4 ฮผg/kg/h
  • inj. lignocaine infusion @1-2 mg/kg/h
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Where

1 site
Sahiwal Medical College Sahiwal
Sahiwal, Pakistan
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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