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โ† Trials
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Effect of Perioperative Oral Rifaximin on Early Graft Dysfunction in Adult Living Donor Liver Transplant

RecruitingNAAges 18 Years - anyAllInstitute of Liver and Biliary Sciences, India
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In plain words

What the trial is, and whether it could suit you

Liver transplantation has been a lifesaving treatment for individuals with end stage liver disease and acute liver failure. However, initial poor function of a liver allograft after liver transplantation, termed early graft dysfunction (EGD), has been associated with increased allograft loss or mortality after transplantation. EGD in LDLT is multifactorial. Factors affecting EGD are GRWR, ischemia reperfusion injury, recipient metabolic demand, graft quality, graft inflow and outflow. Studies shows that the incidence of EGD is 15-38%. It is associated with increased allograft loss \& mortality. Rifaximin is an antibiotic that reduces EGD by 50% as shown by 2 studies but this study was done in DDLT setting and rifaximin was given in the pretransplant group. In this investigators will study the effect of perioperative oral rifaximin on early graft dysfunction in adult living donor liv

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * All recipients (adults) undergoing living donor liver transplant in ILBS. Exclusion Criteria: * Negative consent * Hypersensitivity to Rifaximin * Patients undergoing retransplant * ALF, ACLF * Pediatrics patients * Patients on rifaximin
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What it tests

  • Rifaximin 550 MG
  • SOC
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Where

1 site
Insitute of Liver and Biliary Sciences
New Delhi, India
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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