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Trial in Arrhythmia Radioablation for Ventricular Tachycardia: Single Fraction vs Three Fractions

RecruitingNAAges 18 Years - 90 YearsAllWeill Medical College of Cornell University
NCT06743789 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This is a research study that aims to understand if giving a lower dose of treatment all at once is as effective and safe as dividing it into three smaller doses for patients with a heart condition called refractory ventricular tachycardia (VT). These patients have not exhibited positive responses to conventional medications or procedures. This study aims to explore whether an alternative approach could yield more beneficial outcomes.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥ 18 years * Structural heart disease: 1. Ischemic cardiomyopathy 2. Non-ischemic cardiomyopathy 3. Hypertrophic cardiomyopathy * Refractory VT severity: 1. VT leading to ICD shock with minimum 3 episodes in any 3-month period without reversible cause; 2. Failed or intolerant to antiarrhythmic drug therapy (either amiodarone or ≥ 2 AADs) AND failed ablation (CA) 3. OR ablation (CA) contraindicated * Ability to understand study protocol and to write informed consent * Willing to comply with specified pre-, post- and follow-up testing, evaluations and requirements * Expected to remain available for at least 36 months after enrollment Exclusion Criteria: * Age \< 18 years * Pregnancy * Prior chest radiation therapy
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What it tests

  • Radiation Therapy
  • Radiation Therapy
  • Radiation Therapy
  • Radiation Therapy
  • Radiation Therapy
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Where

1 site
Weill Cornell Medicine
New York, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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