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Transfer Direct System as a New Method for Embryo Transfer

RecruitingNAAges 18 Years - 50 YearsFemalePremium Fertility
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In plain words

What the trial is, and whether it could suit you

Infertility is defined as the inability to conceive within a year of unprotected intercourse. Infertility affects one in six couples and represents a public health problem causing feelings of helplessness, depression, and anxiety in both women and men worldwide. Despite the desire to become parents, up to 50% of infertile couples do not seek medical treatment, and 50-60% abandon treatment after two or three failed in vitro fertilization (IVF) cycles, even when the procedure is covered by insurance or public health. There are multiple reasons for this discontinuation; however, after removing cost considerations, psychological stress and poor prognoses represent the main reasons for stopping treatment. Clinical infertility treatments are generally ineffective. Success remains poor even with IVF, as evidenced by current live birth rates (LBRs) of only \~30% per initiated cycle. The primary

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Patients whose written informed consent is obtained, approved by the Ethics Committees for Investigation with Medicinal Products (ECRmp) after being duly informed of the nature of their disease and after voluntarily accepting the treatment program, knowing the potential risks, benefits, and inconveniences. 2. Patients who are going to undergo ART with a SET and have at least one vitrified euploid blastocyst with PGT-A (Preimplantation Genetic Test for the detection of Aneuploidy). 3. Women of reproductive age between 18 and 50 years (both inclusive) 4. Body mass index (BMI): \<30 kg/m2 5. Absence of adenomyosis and endometriosis 6. Uterus without pathologies that can contraindicate the transfer or may hinder implantation (e.g., polyps, fibroids that come into contact with the cavity, or Asherman syndrome) or without a history of thin endometrium or irregular patterns in thin endometrial preparations. 7. Absence of immune pathologies (e.g., lupus) that could endanger the health of the patient. 8. Easy transfer test or history of embryo transfer without difficulty or factors that indicate that the transfer is easy. Exclusion Criteria: 1. Difficult or very painful transfer tests. 2. Pathologies of an oncological nature. 3. The existence of serious or uncontrolled bacterial, fungal, or viral infections that, in the opinion of the principal investigator, may interfere with the patient's participation in the study or the evaluation of its results. 4. Other circumstances or difficulties that, in the opinion of the investigator, may pose a risk to the subject or reduce the chances of obtaining satisfactory data to achieve the objectives of the study, such as a history of severe preeclampsia without assessment by the obstetric team, psychiatric pathologies without prior assessment by the psychiatrist, uncontrolled or destabilized cardiac pathologies.
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What it tests

  • Transfer Direct System (TDS)
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Where

4 sites
Dexeus Mujer Barcelona
Barcelona, Spain
Clínica FIV Valencia
Valencia, Spain
Clínica Vida Recoletas Sevilla
Seville, Spain
Clínica Next Fertility Valencia
Valencia, Spain
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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