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โ† Trials
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Fast Discharge After Acute Myocardial Infarction Discharge MI

RecruitingNAAges 18 Years - anyAllMedical University Innsbruck
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In plain words

What the trial is, and whether it could suit you

To evaluate the hypothesis that a fast discharge strategy (discharge at 24 \[ยฑ 12\] hours) following invasive management for acute myocardial infarction is non-inferior to standard of care (\>36 hours) with respect to the risk of major adverse cardiovascular events (MACE) during follow-up.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Uncomplicated acute myocardial infarction (NSTEMI and STEMI) diagnosed according to the 2023 acute coronary syndrome guidelines of the ESC * Age โ‰ฅ 18 years at time of consent * Invasive management strategy and in case of PCI successful intervention of the culprit lesion defined by post-interventional TIMI 3 flow * Ability to understand and willingness to sign and date written informed consent Exclusion Criteria: * Myocardial infarction complicated by cardiac arrest (out-of-hospital cardiac arrest/in-hospital cardiac arrest) * PCI-related complications (coronary perforation, side branch closure, inability to deliver stent/balloon, aortic dissection, allergic reaction grade โ‰ฅ2, stroke/thromboembolism, access site complications including pseudoaneurysm, arteriovenous fistula, retroperitoneal hemorrhage and arterial dissection/occlusion or emboli) * Malignant arrhythmias including sustained ventricular arrhythmias and persistent bradycardia (\< 50 beats per minute due to sinus node or atrioventricular conduction system abnormalities, second- /third-degree atrioventricular block) after PCI * Ongoing hemodynamic instability (systolic blood pressure \<90 mmHg, elevated lactate concentrations, need for inotropes or vasopressors) * Ongoing respiratory instability defined by Killip class \>I (rales, pulmonary edema) * Ongoing quantitative disorders of consciousness (somnolence, sopor, coma) * Acute kidney injury defined by Kidney Disease Improving Global Outcomes (KDIGO) stages 2 and 3 * Pregnancy * Untreated critical non-culprit lesions requiring revascularization during index hospitalization not allowing fast discharge * Immobility/limited mobility or social circumstances that prevent fast discharge assessed by an interprofessional care team
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What it tests

  • Fast discharge strategy
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Where

8 sites
Hospital Wiener Neustadt
Wiener Neustadt, Austria
Cardinal Schwarzenberg Hospital Schwarzach
Schwarzach im Pongau, Austria
Paracelsus Medical University Salzburg
Salzburg, Austria
Medical University of Graz
Graz, Austria
Medical University of Innsbruck
Innsbruck, Austria
University Teaching Hospital Wels-Grieskirchen
Wels, Austria
Academic Teaching Hospital Feldkirch
Feldkirch, Austria
Ludwig Maximilian University Munich
Munich, Germany
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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