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Processed Electroencephalography-guided General Anesthesia and Outcomes in Major Abdominal Surgery

RecruitingNAAges 18 Years - 70 YearsAllAssiut University
NCT06753409 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study aims to evaluate whether the reduction in the amount of intraoperative norepinephrine required to prevent hypotension, facilitated by processed electroencephalography (pEEG) -guided general anesthesia, will lead to a decrease in postoperative complications, particularly acute kidney injury (AKI).

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Patients scheduled for major abdominal surgery lasting more than 2 hours under general anesthesia. 2. American Society of Anesthesiologists Physical Status (ASA) score I-III. 3. Age range of 18-70 years. 4. Both male and female patients. Exclusion Criteria: 1. Emergency surgeries. 2. Uncontrolled hypertension (systolic blood pressure \>150 mm Hg) despite medication. 3. Recent acute cardiovascular events, including heart failure or acute coronary syndrome. 4. Chronic kidney disease with a glomerular filtration rate \<30 ml/min/1.73 m² or requiring renal replacement therapy. 5. Severe hepatic failure (ASAT/ALAT \>2N, elevated bilirubin, or PT \<50%). 6. Preoperative sepsis or septic shock. 7. Pregnancy. 8. Patient refusal to participate in the study.
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What it tests

  • Processed electroencephalography (pEEG) Guided General Anesthesia
  • Non-pEEG-Guided General Anesthesia (with blinded pEEG monitoring)
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Where

1 site
Assiut University Hospitals
Asyut, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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