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Respiratory Functions, Thoracoabdominal Movements and Exercise Capacity in Neuromuscular Diseases

Recruitingn/aAges 5 Years - 15 YearsAllLokman Hekim University
NCT06756633 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The clinical trial titled "Investigation of Respiratory Functions, Thoracoabdominal Movements, and Exercise Capacity in Neuromuscular Diseases" aims to evaluate the respiratory functions, thoracoabdominal movements, and exercise capacity in children with Duchenne Muscular Dystrophy (DMD) and Spinal Muscular Atrophy (SMA) compared to healthy controls. The study will use spirometry, structured light plethysmography (SLP), the six-minute walk test, and the six-minute pegboard ring test to assess these functions. This trial will be conducted at the Lokman Hekim University Muscle and Nerve Diseases Application and Research Center from May 2024 to Dec 2025.

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📋 Eligibility rules (as published)
1. Duchenne Muscular Dystrophy (DMD) -Inclusion Criteria: Clinically diagnosed with Duchenne Muscular Dystrophy. Age above 5 years. Able to breathe independently. Willing to participate in the study. -Exclusion Criteria: Presence of cognitive problems that affect the assessment results. History of pulmonary surgery. Advanced heart failure. 2. Spinal Muscular Atrophy (SMA) -Inclusion Criteria: Clinically diagnosed with Spinal Muscular Atrophy. Age above 5 years. Able to breathe independently. Willing to participate in the study. -Exclusion Criteria: Presence of cognitive problems that affect the assessment results. History of pulmonary surgery. Advanced heart failure. 3. Healthy Controls * Inclusion Criteria: No diagnosis of neuromuscular diseases. Age above 5 years. Able to breathe independently. Willing to participate in the study. -Exclusion Criteria: Presence of cognitive problems that affect the assessment results. History of pulmonary surgery. Advanced heart failure.
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What it tests

  • Respiratory Function Test
  • Structured light plethysmography
  • 6 Minute Walking Test
  • 6-Minute Peg Board Ring Test
  • Hand Grip Strength
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Where

1 site
Lokman Hekim University
Ankara, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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