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Post Extraction Changes After Alveolar Socket Preservation Using Autogenous Dentin Graft (ADG) Combined With Either Albumin Platelet-rich Fibrin (ALB-PRF) or Standard Platelet-rich Fibrin (PRF).

RecruitingNAAges 18 Years - 60 YearsAllKafrelsheikh University
NCT06757218 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The study focuses on the impact of tooth loss on alveolar bone, which shrinks significantly within the first three months. To prevent this, strategies like alveolar ridge preservation are used. Autogenous dentin, taken from the patient, supports healing and bone regrowth. Platelet-rich fibrin (PRF), made from the patient's blood, enhances healing and bone density by releasing growth factors. A new technique combining L-PRF with albumin creates a stable healing membrane that provides a steady release of growth factors. Overall, these methods improve recovery after tooth extractions and prepare sites for future dental work.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Medically free patients. * Adult patients above 18 Years to 60 Years. * Non-restorable tooth indicated for extraction. * Posterior mandibular teeth. * Inactive infection related to the tooth. * Cooperative patients. Exclusion Criteria: * Presence of any systemic disease that could influence the outcome of the therapy. * Presence of any risk factor (smoker, pregnant and lactating patients). * Patients with bone diseases. * Patients with poor oral hygiene.
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What it tests

  • empty socket
  • Autogenous Dentin Graft with Platelet Rich Fibrin
  • Autogenous Dentin Graft with Albumin Platelet Rich Fibrin
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Where

1 site
Kaferelsheikh University
Kafr ash Shaykh, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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