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Central Motor Mechanisms in AIS Via HD-sEMG, EEG and Neuromuscular Coupling Analysis

Recruitingn/aAges 10 Years - 18 YearsAllThe First Affiliated Hospital of Zhejiang Chinese…
NCT06758115 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

1. Verifying the Motor Control Effects of Spinal Manipulation on AIS Using outpatient and inpatient AIS patients from our department as the study subjects, standardized spinal manipulation treatment is applied. The efficacy is evaluated through a combination of clinical outcome measures, HD-EMG for paraspinal muscle function assessment, and Pro-Kin balance system for trunk stability analysis. This establishes an AIS efficacy platform to further clarify the effectiveness of spinal manipulation in motor control regulation of AIS. 2. Investigating the Central Motor Network's Response to Spinal Manipulation in AIS Utilizing high-density sEMG-EEG technology, synchronized brain and muscle electrical signals are collected before and after treatment. By employing a neuromuscular synchronization and coupling analysis approach that integrates linear and nonlinear methods, the characteristic indice

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Patients aged ≥10 years; 2. Risser sign grade 0-3; 3. Cobb angle between 10° and 40°; 4. No prior treatment; 5. Female patients within 1 year after menarche or before menstruation; 6. The patient's guardian signs the informed consent form for treatment. Exclusion Criteria: 1. Those who do not meet the diagnostic criteria for AIS or inclusion criteria; 2. Patients with severe primary diseases such as cardiovascular, cerebrovascular, liver, kidney, and hematopoietic system disorders, or those with mental illnesses; 3. Patients with thrombocytopenia, coagulation disorders, or a tendency to bleed; 4. Patients who are afraid of the treatment and cannot tolerate it; 5. Those who have already received other treatments that may affect the study's outcome measures.
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What it tests

  • Tuina (Massage) Therapy
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Where

1 site
the First Affiliated Hospital of Zhejiang Chinese Medical University
Hangzhou, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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