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Intranasal Nafarelin For Triggering Oocyte Maturation

RecruitingPhase 4Ages 18 Years - 40 YearsFemaleFundacion Dexeus
NCT06763926 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This is a non-inferiority randomised, controlled clinical trial comparing subcutaneous triptorelin to intranasal nafarelin for the final maturation of oocytes in women undergoing fertility preservation cycles with oocyte cryopreservation undergoing ovarian stimulation.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Women undergoing fertility preservation cycles with oocyte cryopreservation * Undergoing a progesterone-primed ovarian stimulation cycle (PPOS) with any commercially available gonadotropin preparation(s) * BMI 18 - 30 kg/m2 Exclusion Criteria: * Allergy or hypersensitivity to either of the study drugs * Hypopituitarism * Known pituitary tumour * Contraindication to intranasal medication administration * Previous poor response to agonist trigger
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What it tests

  • Subcutaneous Triptorelin
  • Intranasal nafarelin
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Where

5 sites
Dexeus Mujer Sabadell
Sabadell, Spain
Dexeus Mujer Sant Cugat
Sant Cugat del Vallès, Spain
Dexeus Mujer Reus
Reus, Spain
Departamento de Ginecología Obstetricia y Reproducción. Hospital Universitari Dexeus
Barcelona, Spain
Dexeus Mujer Tarragona
Tarragona, Spain
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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