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The Effect of a Mediterranean Diet on Quality of Life in Multiple Sclerosis Patients

RecruitingNAAges 18 Years - 70 YearsAllTel-Aviv Sourasky Medical Center
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In plain words

What the trial is, and whether it could suit you

The role of dietary interventions in improving symptoms of multiple sclerosis (MS) is of high interest amongst patients and researchers, but data supporting this evidence are limited. Current evidence indicates that A higher Expanded Disability Status Scale (EDSS) score correlates with poor diet quality in patients with MS. Moreover, even though disease-modifying therapies (DMT) improve disease course and prognosis, MS patients report a lower quality of life (QoL) than people without illness. The Mediterranean diet (Med-Diet) is beneficial in preventing cardiovascular comorbidities, and outcomes of a decrease in inflammation processes are evident. Recent studies suggest that the Med-Diet might positively affect MS QoL, However, empirical evidence remains unclear, limiting the possibility of evidence-based nutritional recommendations. In the current study, we aim to investigate the effect

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Confirmed MS based on 2017 Mcdonald criteria, with stable medication regimen in the previous six months. Exclusion Criteria: * Pregnancy or lactating * People with a lack of judgment * Serum creatinine โ‰ฅ2 mg/dL(177 ฮผmol per liter) or more * Patients who had gastrointestinal problems that would prevent them from following any of the test diets * Patients who had liver dysfunction (an increase by a factor of at least two above the upper limit of normal in alanine aminotransferase and aspartate aminotransferase levels) * Active cancer or chemotherapy treatment in the last three years.
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What it tests

  • Mediterranean Medical Nutrition Therapy (counselling)
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Where

1 site
Tel Aviv Sourasky medical center
Tel Aviv, Israel
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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