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Comparison of MIST With PRF and GBT With PRF in the Treatment of Intrabony Periodontal Defect. A Prospective RCT

RecruitingNAAges 18 Years - 65 YearsAllSemmelweis University
NCT06768424 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The aim is to evaluate in a prospective, randomized, controlled clinical study the healing of a MIST procedure combined with PRF, or GBT combined with PRF. Clinical, radiological evaluation of the regenerative surgical method and the GBT non-surgical therapy in solitaire deep intrabony periodontal defect.

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📋 Eligibility rules (as published)
Inclusion Criteria: * solitaire intrabony periodontal defect at least 4 mm Exclusion Criteria: * Periodontitis with intrabony defect (Intrabony component ≥ 4mm, defect radiological angulation \> 25°, * The patient is able to comply with the study -related procedures (i.e. good level of oral hygiene, follow-up procedures). * Patients must not be heavy smokers (\<5 cigarettes/day). * furcation involvement * Full mouth plaque and bleeding scores (FMPS and FMBS) of \<15% (O'Leary et al. 1972). * The patient is able to fully understand the nature of the study, signed informed consent.
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What it tests

  • Guided biofilm therapy
  • Platelet Rich Fibrin
  • Minimally Invasive Surgical Technique
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Where

1 site
Semmelweis University Department of Periodontology
Budapest, Hungary
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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