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The Use of Acupuncture to Reduce Chemotherapy Induced Peripheral Neuropathy in Gynaecological Cancer Patients

RecruitingNAAges 18 Years - anyFemaleKaren Kar Loen CHAN
NCT06769061 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Objectives: To explore the feasibility and effectiveness of acupuncture on reducing Chemotherapy Induced Peripheral Neuropathy (CIPN) in gynaecological cancer patients who have received carboplatin and paclitaxel chemotherapy combination. Results of this pilot trial will provide preliminary information for a potential a larger scale multicentre study. Hypothesis: Acupuncture can significantly reduce CIPN in gynaecological cancer patients treated with chemotherapy Design and subjects: This is a pilot, prospective randomised controlled trial. This is an exploratory trial to evaluate the feasibility and effectiveness of acupuncture in reducing CIPN in gynaecological cancer patients. Eligible patients will be 1:1:1 randomised to three groups: electroacupuncture group, sham acupuncture group and waiting-list (usual care) control group. For electroacupuncture and sham acupuncture groups,

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age 18 or above * Diagnosis of uterine (endometrial) cancer, ovarian cancer and cervical cancer * ECOG=0-2 * Life expectancy of \> 6 months * Completed at least 6 cycles of carboplatin or cisplatin chemotherapy together with paclitaxel at least 3 months before joining the study * Able to read and understand the questionnaires * PNQ score of C or above Exclusion Criteria: * Bleeding tendency * Abnormal clotting profile * Platelet lower than 50 * Received acupuncture in the past * Currently receiving chemotherapy treatment * Known neurological disorders or pre-existing neuropathy unrelated to chemotherapy * Routinely take aspirin or any anticoagulant drugs * Having active skin infection * With pacemaker
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What it tests

  • Acupuncture
  • sham acupuncture
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Where

1 site
Department of Obstetrics and Gynaecology
Hong Kong, Hong Kong
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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