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โ† Trials
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Brain Stimulation for Foot-sole Sensation in Older Adults With Foot-sole Somatosensory Deficits

RecruitingNAAges 65 Years - anyAllHebrew SeniorLife
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In plain words

What the trial is, and whether it could suit you

In older adults, diminished sensation of the legs and feet is highly prevalent and causes poor balance and reduced mobility. This type of sensation is not only dependent upon the receptors and nerves in the legs and feet, but also upon a complex central nervous system pathway that includes the cerebral cortex of the brain. This project will use a form of noninvasive brain stimulation called transcranial direct current stimulation (tDCS) to test whether increasing the excitability of the brain networks that process sensory feedback can augment foot sole sensation, balance, and mobility in older adults suffering from mild-to-moderate foot sole sensory impairments.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: 1. Aged โ‰ฅ65 years. 2. Self-reported feeling of unsteadiness or difficulty when standing and walking. 3. Mild-to-moderate foot-sole somatosensory impairment: the ability to perceive 75g monofilament but inability to perceive 10g monofilament. Exclusion Criteria: 1. self-reported inability to stand or walk continuously for one minute without personal assistance (canes or walkers allowed); 2. history or presence of foot ulceration, amputation, or deformities; 3. self-reported uncontrolled pain or pain that is associated with mobility disability; 4. uncontrolled diabetes mellitus; 5. hospitalization within the past three months due to acute illness, or as the result of a musculoskeletal injury significantly affecting balance; 6. persistent severe pain of lower extremity when standing or walking; 7. diagnosis of dementia, Parkinson's disease, or stroke that affects balance; 8. unstable medical condition; 9. legal blindness or deafness; 10. uncontrolled hypertension (i.e., systolic BP \>180, diastolic BP \>100 mm Hg, or prescription of โ‰ฅ3 anti-hypertensive medications); 11. functionally limiting nephropathy, severe diseases or transplant of the kidney or liver, renal or congestive heart failure; 12. active cancer treatment; 13. balance disorders due to past use of chemotherapy or history of Guillain-Barrรฉ syndrome; 14. use of neuro-active or recreational drugs (e.g., sedatives, anti-psychotics), or alcohol abuse, which may affect the brain excitability; 15. contraindications to MRI or tDCS (e.g., personal or family history of seizures or epilepsy, metallic or electric bio-implants, claustrophobia, brain surgery); 16. persistent vertigo; 17. history of Charcot-Marie-Tooth nerve disease.
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What it tests

  • transcranial direct current stimulation
  • active sham stimulation
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Where

1 site
Hebrew SeniorLife
Roslindale, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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