Virtual Reality As Adjunct Therapy for Vaso-Occlusive Pain

Inclusion Criteria: 1. Patient ≥ 8 up to 21 years of age 2. Presenting to CHNOLA ER or outside facility with chief complaint of vaso-occlusive pain crisis, requiring inpatient admission for further pain management 3. No known cognitive or neurological deficits 4. Parental/guardian permission (informed consent) and if appropriate, child assent. Exclusion Criteria: 1. Patients aged 7-years-old and younger. 2. Patents upon admission found to have sequela of their sickle cell disease that would require medical therapy greater than the standard of care for a vaso-occlusive pain event. This includes acute chest syndrome, splenic sequestration, post-operative pain, and/or cerebrovascular accident 3. Patients who are developmentally or cognitively incapable of using VR equipment and answering questions appropriately 4. Failure to obtain or refusal to provide parental/guardian permission (informed consent) and if appropriate child assent 5. Patient has previously participated in the study 6. Study team is unable to initiate study interventions within the first 24 hours of a patient's admission