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Comparing Prophylactic Intravenous Pethidine and Intrathecal Pethidine in Preventing Post Spinal Shivering in Caesarean Section

RecruitingPhase 3Ages 20 Years - 40 YearsFemaleAlexandria University
NCT06775431 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to assess the effect of IV pethidine and intrathecal pethidine on the incidence, onset, duration, and intensity of shivering in females undergoing caesarean section. The main question it aims to answer is: which route is more efficacious in preventing shivering. Researchers will compare IV pethidine and intrathecal pethidine to see their effects on post spinal shivering, their effects on hemodynamic stability, nausea, vomiting, and sedation.

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📋 Eligibility rules (as published)
Inclusion Criteria: \- Exclusion Criteria: 1. contraindications to spinal 2. uncontrolled hypertension, diabetes mellitus, hepatic, pulmonary diseases, and thyroid disease 3. obesity (BMI \>35) 4. drug allergy 5. temperature below 36 degrees celcius or above 37.5 degrees celcius
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What it tests

  • Pethidine Hydrochloride 50 Mg/mL Solution for Injection
  • Pethidine Hydrochloride 50 Mg/mL Solution for Injection administered intrathecally
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Where

1 site
El-Shatby University Hospital
Alexandria, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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