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MR Elastography for Assessing Liver Fibrosis in Chronic Hepatitis B

Recruitingn/aAges 18 Years - 80 YearsAllShengjing Hospital
NCT06779058 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

How to construct a non-invasive, accurate, and convenient method to evaluate the severity of liver fibrosis (LF) is an important general problem in the management of patients with chronic hepatitis B (CHB). We plan to investigate the ability of magnetic resonance elastography (MRE) to grade fibrosis in chronic hepatitis B and apply to clinical longitudinal follow-up.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥ 18 years old * Confirmed CHB (laboratory, imaging and clinical tests) * MRE within 6 months before and after liver biopsy * Treatment-naïve * Child-Pugh Grade A (\<7 points) * Written informed consent in prospective follow-up cohort Exclusion Criteria: * Patients with liver malignant tumor * Chronic hepatitis due to other causes (such as alcoholic hepatitis) * CHB combined with hepatitis C, hepatitis D, or HIV * Patients with biliary tract diseases * Contraindications of MRE examination, MRE failure * Poor pathological effect
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What it tests

  • MRE
  • Liver biopsy
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Where

1 site
Shengjing Hospital
Shenyang, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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