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Continuous Versus Single Injection Adductor Canal Blocks for Outpatient Total Knee Arthroplasty

RecruitingPhase 4Ages 18 Years - anyAllUniversity of California, San Diego
NCT06784882 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This is a single-center pilot study to determine if an adductor canal continuous nerve block is superior to single injection nerve block following total knee arthroplasty. Investigators will randomize participants to either continuous nerve block or single injection nerve block for the adductor canal preoperatively. They will assess differences in pain (measured in numeric rating scale), opioid consumption, and physical therapy milestones from postoperative day 0 to 7.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Adult participants of at least 18 years of age 2. Undergoing a primary, unilateral, total knee arthroplasty 3. Planned single-injection adductor canal nerve block 4. Weight \> 50 kg (to minimize the risk of local anesthetic toxicity) Exclusion Criteria: 1. chronic opioid or tramadol use: daily oxycodone equivalents \> 20 mg for \> 4 weeks 2. neuro-muscular deficit of the surgical limb 3. moderate pain (NRS \> 3) in an anatomic location other than the surgical site 4. planned hospital admission following surgery 5. history of opioid misuse 6. those who lack capacity to complete informed consent 7. inability to contact the investigators during the treatment period, and vice versa (e.g., lack of telephone access) 8. incarceration 9. pregnancy 10. allergy to amide local anesthetics
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What it tests

  • continuous peripheral nerve block with OnQ pump
  • single injection nerve block
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Where

1 site
University of California, San Diego
La Jolla, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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