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Optimizing an Extended Care Intervention to Promote Weight Loss Maintenance

RecruitingNAAges 18 Years - anyAllUniversity of Alabama at Birmingham
NCT06785064 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The purpose of this study is to find out what combination of components, if any, offers the best support for keeping weight off after someone loses weight. Long term weight loss maintenance is a challenge for many people who lose weight. There are many strategies, or components, people may use to avoid regain, but investigators do not know if there is a best, or optimal, combination of such components that can be done without adding a lot of cost or other burdens for people. * The primary goal of this clinical trial is to identify the optimal package that maximizes weight loss maintenance. * The study also wants to understand the reasons why these components may work and if certain components help specific sub-groups of people. Participants will engage in a 16-week Phase 1 Weight Loss Program. Participants who lose 5% or more of their weight during that program will continue to Phase 2

Sign in to get the eligibility rules as simple questions to take to your doctor.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age \>18 years * Body mass index (BMI) \>30 kg/m2 * Has regular access to internet (to access Zoom videoconferencing platform) * If indicated during screening, willing to obtain medical clearance for exercise from their healthcare provider prior to enrollment Exclusion Criteria: * Current or recent (past 6 months) use of prescription weight loss medications * Weight loss \>10 pounds in past 6 months (other than postpartum) * Pregnancy or anticipating pregnancy * Another household member already participating in the study * Participation in another randomized research project * Uncontrolled hypertension (blood pressure \>160/100 mm Hg at screening) * Any of the following other medical conditions: myocardial infarction or cerebrovascular accident within the last 6 months; unstable angina within the past 6 months; NYHA Class III or IV congestive heart failure; type 1 diabetes; and chronic lung diseases that limit physical activity * Unable to identify potential buddy (i.e., adult friend or family member) for extended care intervention phase * Residing \>50 miles from the university (to attend assessment visits) * Planning to relocate out of the area in the next 18 months * Does not have internet access * Unwilling or unable to do any of the following: give informed consent; read/understand English; accept random assignment
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What it tests

  • Reduced Food Variety (RFV)
  • Home-based Resistance Training (HBRT)
  • Buddy Training and Support (BTS)
  • Acceptance and Commitment (ACT) Workshops
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Where

1 site
University of Alabama at Birmingham
Birmingham, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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