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A Clinical Study on the Benefits of Carbon Nanoparticles Injection Time in Patients With Thyroid Cancer.

RecruitingPhase 3Ages 16 Years - 80 YearsAllSecond Affiliated Hospital of Xi'an Jiaotong Univ…
NCT06791005 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The detection rate of thyroid cancer (PTC) has increased rapidly in recent years. Except undifferentiated cancer, surgery is still one of the most important treatments for all types of thyroid cancer, and there is a consensus to use the lobes of the gland as the minimum extent of resection. In the meantime, a basic consensus has been reached that central zone lymph node (VI) dissection is the minimum extent of lymph node dissection. In clinical practice, neck surgery and lumpectomy are mostly performed. Hypoparathyroidism and recurrent laryngeal nerve injury are the most common complications of radical surgery for thyroid cancer, both in open surgery and the luminal approach. Once these complications occur, they have a serious impact on the quality of life of patients in the postoperative period. A number of contrast agents are now being used to help minimize complications. Carbon nanopa

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📋 Eligibility rules (as published)
Inclusion Criteria: * Preoperative pathological assessment indicated the presence of thyroid cancer with a maximum diameter of less than 4 cm. * Postoperative pathological evaluation confirmed bilateral thyroid cancer or lateral lymph node metastasis. * Vocal cord examination conducted one week prior to surgery revealed no abnormalities. * The patient had no history of prior thyroid surgery and required a total thyroidectomy. * Blood pressure was stably controlled. * The patient regained consciousness and was able to communicate normally. Exclusion Criteria: * Prior to enrollment, the patient had received radiotherapy, chemotherapy, or isotope therapy. * A documented history of thyroid surgery. * Age under 16 years. * Known allergies to the medications under investigation or an inability to tolerate surgical intervention. * Presence of a retrosternal thyroid tumor. * Tumor invasion of the parathyroid glands and/or the recurrent laryngeal nerve during surgical procedures. * Postoperative pathology suggestive of medullary carcinoma or undifferentiated carcinoma. * Development of a postoperative tracheal fistula.
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What it tests

  • Preoperative Injection of Carbon Nanoparticles
  • Intraoperative Injection of Carbon Nanoparticles
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Where

1 site
The Second Affiliated Hospital of Xi'an Jiaotong University
Xi'an, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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