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Diagnosis, Treatment, and Outcome Assessment of Septic Cardiomyopathy Using an Integrated Mathematical Model

Recruitingn/aAges 18 Years - anyAllVilnius University
NCT06793020 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this observational study is to evaluate whether a new integrated mathematical model can improve the accuracy of diagnosing septic cardiomyopathy and predicting clinical outcomes in adult patients with suspected septic cardiomyopathy. The study aims to determine whether the integrated mathematical model enhances diagnostic accuracy and improves the prediction of clinical outcomes in these patients.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age 18 years or older; * Sepsis according to SEPSIS-3 criteria: * Suspected/confirmed infection and * SOFA (Sequential Organ Failure Assessment) score ≥ 2 or qSOFA score ≥ 2; * Septic shock according to SEPSIS-3 criteria: * Sepsis is diagnosed and * Vasopressor infusion is used to maintain a mean arterial pressure (MAP) ≥ 65 mmHg and * Lactate \> 2 mmol/l; * Cardiovascular support requirement for norepinephrine \> 0.1 mcg/kg/min infusion; * Signed informed consent form (ICF); Exclusion Criteria: * Individuals under 18 years of age; * Has uncompensated cardiovascular disease: * Cardiogenic shock; * Congenital heart disease; * Heart failure NYHA functional class IV; * Refusal to participate in the study.
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What it tests

  • Not listed
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Where

2 sites
Vilnius University Hospital Santaros Klinikos
Vilnius, Lithuania
University Clinical Centre of the Medical University of Warsaw
Warsaw, Poland
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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